Seth Rogen recently appeared on “Watch What Happens Live” and wrestled with the prospect of making a sequel to “The Pineapple Express,” his beloved 2008 stoner comedy that grossed more than $100 million at the worldwide box office.

Rogen and Franco, 47, made a number of comedies together in the 2000s and 2010s. They even famously included a miniature parody-style sequel to Pineapple Express in their 2013 disaster comedy This Is The End.

Pineapple Express 2 is a sequel that fans of the first film have reportedly been waiting for years. The first film was directed by David Gordon Green and was released theatrically on August 8, 2008, by Sony Pictures Releasing. It was produced by Judd Apatow and Shauna Robertson. Here's the official synopsis as per Letterboxd,

So it stands to reason that Seth Rogen would be asked (again) whether we'll ever get a sequel to The Pineapple Express. After all, The Pineapple Express is the most commercially successful movie that Rogen ever made with James Franco.

When Pineapple Express starring Seth Rogen hit cinemas in 2008, it quickly became one of the most memorable stoner comedies.

Rogen stars in the film as Dale Denton, a process server who unknowingly becomes best friends with drug dealer Saul Silver (James Franco). The comedy was written by Rogen, Judd Apatow, and Rogen's longtime collaborator,

Seth Rogen, who starred in Pineapple Express alongside former BFF James Franco, reacted to the idea of a sequel to the 2008 movie, despite their falling out.

In an appearance on Watch What Happened Live, Rogen talked about the possibility of the 2008 stoner movie getting a sequel after host Andy Cohen read a fan question bringing up the topic, according to Deadline .